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(1R)-3,3μ-Bis[2,4,6-Tris(1-Methylethyl)Phenyl]-1,1μ-Binaphthalene-2,2μ-Diol CAS NO 247123-09-7


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CAS No.:247123-09-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1R)-3,3μ-Bis[2,4,6-Tris(1-Methylethyl)Phenyl]-1,1μ-Binaphthalene-2,2μ-Diol is a sophisticated chiral ligand and catalyst precursor, widely recognized for its pivotal role in asymmetric synthesis. This compound matters for its exceptional ability to induce high enantioselectivity in a variety of organic transformations, enabling the production of single-enantiomer intermediates crucial for advanced materials and pharmaceuticals. Industries involved in fine chemical synthesis, pharmaceutical R&D, and advanced material science require this high-performance ligand to develop novel, optically active compounds.

Application

  • As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, Diels-Alder, and allylic substitution.
  • Key precursor for constructing BINOL-derived phosphoric acid catalysts used in organocatalysis.
  • Critical component in the synthesis of pharmaceutical intermediates requiring high enantiomeric purity.
  • Utilized in the development of advanced materials such as chiral polymers and liquid crystals.
  • Employed in academic and industrial research for method development in stereoselective synthesis.
  • Facilitates asymmetric carbon-carbon bond formation reactions.

Basic Information

Item Details
Product Name (1R)-3,3μ-Bis[2,4,6-Tris(1-Methylethyl)Phenyl]-1,1μ-Binaphthalene-2,2μ-Diol
CAS No. 247123-09-7
Molecular Formula C52H58O2
Molecular Weight 714.99 g/mol
Synonyms (R)-3,3'-Bis(2,4,6-Triisopropylphenyl)-1,1'-binaphthyl-2,2'-diol; (R)-3,3'-Triisopropylsilyl-BINOL; (R)-3,3'-TriIPS-BINOL; (R)-TRIP; (R)-3,3'-Bis(2,4,6-Triisopropylphenyl)-BINOL; (R)-3,3'-TIPS-BINOL; (R)-3,3'-Bis(triisopropylphenyl)-2,2'-dihydroxy-1,1'-binaphthyl; (1R)-3,3'-Bis[2,4,6-Tris(1-methylethyl)phenyl]-[1,1'-binaphthalene]-2,2'-diol
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Quality Control

Our production of (1R)-3,3μ-Bis[2,4,6-Tris(1-Methylethyl)Phenyl]-1,1μ-Binaphthalene-2,2μ-Diol adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and chiral analysis, to confirm identity, assay, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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