Description

2,3-Difluoro-4-(trifluoromethyl)phenylacetic acid is a high-value fluorinated aromatic building block. This compound is critical for introducing specific fluorine-substituted phenylacetic acid motifs into complex molecular architectures, enabling the fine-tuning of physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its unique fluorination pattern can enhance metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved lipophilicity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Organic Electronics: Employed in the development of novel materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Advanced Material Science: Acts as a building block for specialty polymers and coatings with enhanced chemical resistance and performance characteristics.
• Chemical Research & Development: A versatile reagent for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	2,3-Difluoro-4-(trifluoromethyl)phenylacetic Acid
CAS No.	247113-95-7
Molecular Formula	C9H5F5O2
Molecular Weight	240.13 g/mol
Synonyms	[2,3-Difluoro-4-(trifluoromethyl)phenyl]acetic Acid; 2-(2,3-Difluoro-4-(trifluoromethyl)phenyl)acetic Acid; α,2,3-Trifluoro-α-(trifluoromethyl)benzeneacetic Acid; 2,3-Difluoro-4-trifluoromethylphenylacetic Acid; 247113-95-7; Benzeneacetic acid, 2,3-difluoro-α,α,α,4-tetrafluoro-; DFTMPAA
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-(trifluoromethyl)phenylacetic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.