Description

4-Amino-6-(Trifluoromethyl)Quinoline is a high-purity, functionalized quinoline derivative characterized by its amino and trifluoromethyl substituents, which impart unique electronic and steric properties. This compound serves as a versatile and critical pharmaceutical intermediate and organic building block for advanced synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides, leveraging the biological activity of the quinoline scaffold and the metabolic stability conferred by the trifluoromethyl group.
• Material Science & OLED Development: Acts as an electron-transporting or hole-blocking material in the design of organic light-emitting diodes (OLEDs) and other electronic materials due to its rigid, planar structure and tunable electronic properties.
• Ligand Synthesis in Catalysis: Employed to create novel nitrogen-containing ligands for transition metal catalysts used in cross-coupling and other asymmetric synthesis reactions.
• Fluorescent Probe & Dye Chemistry: Serves as a core structure for synthesizing advanced fluorescent tags, sensors, and dyes for bio-imaging and analytical applications.

Basic Information

Product Name	4-Amino-6-(Trifluoromethyl)Quinoline
CAS No.	247113-89-9
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	6-(Trifluoromethyl)quinolin-4-amine; 4-Amino-6-trifluoromethylquinoline; 4-Amino-6-(trifluoromethyl)quinoline; Quinoline, 4-amino-6-(trifluoromethyl)-; 6-Trifluoromethyl-4-quinolinamine
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-6-(Trifluoromethyl)Quinoline is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.