Description

Boc-Tyr(Et)-Oh is a protected tyrosine derivative, specifically N-tert-butoxycarbonyl-O-ethyl-L-tyrosine, widely used as a key building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise control over amino acid side-chain reactivity during solid-phase or solution-phase peptide assembly. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for developing therapeutic peptides, diagnostic agents, and novel biochemical tools.

Application

• Peptide Synthesis: A critical intermediate for the controlled incorporation of modified tyrosine residues into peptide chains.
• Pharmaceutical Research: Used in the R&D of peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation: Serves as a precursor for creating labeled peptides or peptide-polymer conjugates for diagnostic and imaging applications.
• Chemical Biology: Employed in the study of protein-protein interactions and signal transduction pathways using synthetic peptide probes.
• Process Development: Used in scaling up the production of complex peptides for clinical and commercial supply.
• Academic & Institutional Research: A standard reagent in university and institutional labs for training and fundamental research in organic and medicinal chemistry.

Basic Information

Product Name	Boc-Tyr(Et)-Oh
CAS No.	247088-44-4
Molecular Formula	C₁₆H₂₃NO₅
Molecular Weight	309.36 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-O-ethyl-L-tyrosine; Boc-O-Ethyl-L-tyrosine; Boc-Tyr(OEt)-OH; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[4-(ethoxy)phenyl]propanoic acid; tert-Butyloxycarbonyl-O-ethyl-L-tyrosine; N-Boc-O-ethyl-L-tyrosine; Boc-L-Tyr(OEt)-OH; Boc-Tyr(Et)-OH
EINECS	Contact for details

Quality Control

Our Boc-Tyr(Et)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to relevant industry standards and can support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-15.0° to -18.0° (c=1 in DMF)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.