Description

1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-(3-Aminopropyl)Hexahydro-2-Oxo-, (3As,4S,6Ar)- is a high-purity, complex heterocyclic organic compound with significant potential in advanced pharmaceutical research and development. Its intricate molecular architecture, featuring fused thienoimidazole and lactam rings with an aminopropyl side chain, makes it a valuable key intermediate or building block for synthesizing novel active pharmaceutical ingredients (APIs). This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or other specialized therapeutic areas.
• Bioconjugation & Probe Development: The reactive primary amine group enables its use in creating bioconjugates, fluorescent probes, or affinity labels for biochemical and diagnostic research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new chemical entities.
• Peptidomimetic Synthesis: The lactam and amide functionalities allow it to act as a constrained scaffold in the design of peptidomimetics, which mimic peptides but with enhanced metabolic stability.
• Chemical Biology Tool Compound: Utilized in target identification and validation studies due to its potential to interact with specific enzymes or receptors.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D programs.

Basic Information

Item	Details
Product Name	1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-(3-Aminopropyl)Hexahydro-2-Oxo-, (3As,4S,6Ar)-
CAS No.	244760-25-6
Molecular Formula	C14H22N4O2S
Molecular Weight	310.42 g/mol
Synonyms	(3aS,4S,6aR)-N-(3-Aminopropyl)hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; Hexahydro-2-oxo-N-(3-aminopropyl)-1H-thieno[3,4-d]imidazole-4-pentanamide, (3aS,4S,6aR)-; Biotin-aminopropyl amide derivative; Vitamin H derivative; 244760-25-6; Biotin-based intermediate; Thienoimidazole lactam amine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity essential for sensitive pharmaceutical R&D. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development under cGMP guidelines for projects requiring regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.