Description

3(2H)-Indolizinone, Hexahydro-2,6,7,8-Tetrahydroxy-5-Methyl-, (2R,5S,6R,7R,8R,8As)- (9Ci) is a complex, stereochemically defined polyhydroxylated indolizinone derivative, a class of compounds known for their significant biological activity. This high-purity chiral building block is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for applications in medicinal chemistry and as a key synthetic intermediate.

Application

• Pharmaceutical Intermediate: Serves as a sophisticated chiral scaffold for the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Biochemical Tool Compound: Acts as a probe or inhibitor in enzymatic and biological pathway studies due to its complex, functionalized structure.
• Asymmetric Synthesis: Employed as a starting material or intermediate in stereoselective synthesis to construct complex natural product analogs.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals and advanced materials requiring high stereochemical purity.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical transformations of polyfunctional molecules.

Basic Information

Item	Details
Product Name	3(2H)-Indolizinone, Hexahydro-2,6,7,8-Tetrahydroxy-5-Methyl-, (2R,5S,6R,7R,8R,8As)- (9Ci)
CAS No.	244612-35-9
Molecular Formula	C9H15NO5
Molecular Weight	217.22 g/mol
Synonyms	(2R,5S,6R,7R,8R,8aR)-Hexahydro-2,6,7,8-tetrahydroxy-5-methyl-3(2H)-indolizinone; Hexahydro-2,6,7,8-tetrahydroxy-5-methyl-3(2H)-indolizinone (stereoisomer); Polyhydroxylated indolizinone derivative; Chiral indolizinone scaffold; CAS 244612-35-9
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We provide comprehensive analytical data to support your research, including HPLC purity, chiral purity analysis, and structural confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is supplied with each shipment, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.