Description

1-Chloro-7-Nitroisoquinoline is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both chloro and nitro substituents on the isoquinoline core, makes it a versatile precursor for constructing complex nitrogen-containing compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a precursor for the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty dyes.
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the isoquinoline moiety into more complex molecules.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	1-Chloro-7-Nitroisoquinoline
CAS No.	244219-94-1
Molecular Formula	C9H5ClN2O2
Molecular Weight	208.60 g/mol
Synonyms	7-Nitro-1-chloroisoquinoline; 1-Chloro-7-nitro-isoquinoline; Isoquinoline, 1-chloro-7-nitro-; 244219-94-1; 1-Chloro-7-nitroisoquinoline; 1-Chloro-7-nitro-isoquinoline
EINECS	Contact for details

Quality Control

Our 1-Chloro-7-Nitroisoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and reliability for your critical synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.