Description

Spiro[2.5]Octane-1-Carboxaldehyde, 4-Methylene-, (1R,3S)-Rel- (9Ci) is a high-purity, stereochemically defined spirocyclic aldehyde building block. This compound matters as a sophisticated chiral intermediate, enabling the synthesis of complex molecular architectures with precise three-dimensional control. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting complex targets.
• Agrochemical Synthesis: Used in the construction of advanced, stereoselective active ingredients for crop protection products.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts.
• Material Science Research: Employed in academic and industrial R&D for creating novel polymers or functional materials with specific spatial configurations.
• Chemical Biology Probes: Useful for synthesizing labeled or tagged compounds to study biological pathways and interactions.
• Process Chemistry Development: Evaluated in scale-up studies for the efficient and stereocontrolled production of target molecules.

Basic Information

Product Name	Spiro[2.5]Octane-1-Carboxaldehyde, 4-Methylene-, (1R,3S)-Rel- (9Ci)
CAS No.	244214-78-6
Molecular Formula	C10H12O
Molecular Weight	148.20 g/mol
Synonyms	(1R,3S)-rel-4-Methylenespiro[2.5]octane-1-carboxaldehyde; rel-(1R,3S)-4-Methylenespiro[2.5]octane-1-carbaldehyde; 4-Methylenespiro[2.5]octane-1-carboxaldehyde, (1R,3S)-rel-; Spiro[2.5]octane-1-carboxaldehyde, 4-methylene-, (1R,3S)-rel-; CAS 244214-78-6
EINECS	Contact for details

Quality Control

Our Spiro[2.5]Octane-1-Carboxaldehyde, 4-Methylene-, (1R,3S)-Rel- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is light-sensitive and easily oxidized; allow the sealed container to reach ambient temperature before opening to minimize moisture ingress and oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.