Description

Methyl 3-[2-Chloro-4-(Trifluoromethyl)Phenyl]Acrylate, also known as Methyl 3-[2-Chloro-4-(Trifluoromethyl)Phenyl]Prop-2-Enoate, is a high-value fluorinated aromatic acrylate ester that serves as a critical synthetic intermediate. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it an essential building block for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and coatings with unique properties like chemical resistance and low surface energy.
• Liquid Crystal & OLED Materials: An important intermediate for synthesizing fluorinated components used in electronic display technologies.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and creating complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical manufacturers for producing client-specific compounds and proprietary substances.

Basic Information

Product Name	Methyl 3-[2-Chloro-4-(Trifluoromethyl)Phenyl]Acrylate
CAS No.	243977-24-4
Molecular Formula	C11H8ClF3O2
Molecular Weight	264.63 g/mol
Synonyms	Methyl 3-[2-Chloro-4-(trifluoromethyl)phenyl]prop-2-enoate; Methyl (2E)-3-[2-Chloro-4-(trifluoromethyl)phenyl]acrylate; (E)-Methyl 3-(2-Chloro-4-(trifluoromethyl)phenyl)acrylate; 2-Propenoic acid, 3-[2-chloro-4-(trifluoromethyl)phenyl]-, methyl ester; Methyl (E)-3-(2-Chloro-alpha,alpha,α-trifluoro-p-tolyl)acrylate; Acrylic acid, 3-(2-chloro-4-(trifluoromethyl)phenyl)-, methyl ester; Methyl trans-3-(2-Chloro-4-trifluoromethylphenyl)acrylate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-[2-Chloro-4-(Trifluoromethyl)Phenyl]Acrylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.