Description

4-Amino-8-(Trifluoromethyl)Quinoline is a high-purity, functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino group and a trifluoromethyl substituent, makes it a versatile intermediate for creating compounds with tailored electronic and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a building block for organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to introduce complex amine functionalities.
• Ligand & Catalyst Development: Utilized to create novel nitrogen-containing ligands for metal complexes used in catalysis.
• Fluorescent Probe Synthesis: Acts as a core structure for developing sensitive fluorescent markers and sensors in analytical chemistry.

Basic Information

Product Name	4-Amino-8-(Trifluoromethyl)Quinoline
CAS No.	243977-15-3
Molecular Formula	C10H7F3N2
Molecular Weight	212.18 g/mol
Synonyms	8-(Trifluoromethyl)quinolin-4-amine; 4-Amino-8-trifluoromethylquinoline; Quinoline, 4-amino-8-(trifluoromethyl)-; 4-Amino-8-(trifluoromethyl)chinolin; 4-Amino-α,α,α-trifluoro-8-quinolinemethane
EINECS	Contact for details

Quality Control

Our 4-Amino-8-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for research and development under cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.