Description

4-Amino-7-(Trifluoromethyl)Quinoline is a high-value, functionalized quinoline derivative characterized by its amino and trifluoromethyl substituents, which impart unique chemical and electronic properties. This compound serves as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the biological activity of the quinoline scaffold.
• Material Science: Serves as a monomer or functional component in the development of advanced organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis: Versatile reagent for constructing complex heterocyclic systems via cross-coupling, cyclization, and functional group transformation reactions.
• Ligand & Catalyst Development: The amino and nitrogen heterocycle functionalities make it suitable for designing novel ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	4-Amino-7-(Trifluoromethyl)Quinoline
CAS No.	243666-11-7
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	7-(Trifluoromethyl)quinolin-4-amine; 4-Amino-7-trifluoromethylquinoline; 4-Amino-7-(trifluoromethyl)quinoline; 7-Trifluoromethyl-4-aminoquinoline; 4-Quinolinamine, 7-(trifluoromethyl)-; Quinoline, 4-amino-7-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Amino-7-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.