Description

7-Methyl-3,4-Dihydro-2H-[1,8]Naphthyridine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. Its value lies in its role as a key building block for synthesizing complex heterocyclic compounds with potential biological activity. This product is essential for research and production teams in the pharmaceutical and agrochemical industries, particularly those focused on developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or insecticides with novel modes of action.
• Medicinal Chemistry: Used extensively in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Organic Synthesis: A versatile reagent for constructing complex naphthyridine-based scaffolds in academic and industrial R&D laboratories.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	7-Methyl-3,4-Dihydro-2H-[1,8]Naphthyridine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	243641-37-4
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	tert-Butyl 7-methyl-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylate; 1,8-Naphthyridine-1-carboxylic acid, 3,4-dihydro-7-methyl-, 1,1-dimethylethyl ester; 7-Methyl-1,2,3,4-tetrahydro-1,8-naphthyridine-1-carboxylic acid tert-butyl ester; 1-Boc-7-methyl-1,2,3,4-tetrahydro-1,8-naphthyridine; 1-(tert-Butoxycarbonyl)-7-methyl-1,2,3,4-tetrahydro-1,8-naphthyridine
EINECS	Contact for details

Quality Control

Our 7-Methyl-3,4-Dihydro-2H-[1,8]Naphthyridine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.