Description

4(3H)-Quinazolinone, 3-[4-(2-Chloroethoxy)Phenyl]-8-Methoxy-2-(4-Methoxyphenyl)- is a high-purity, synthetic organic compound belonging to the quinazolinone class, a scaffold of significant pharmaceutical interest. This advanced intermediate is valued for its precise molecular architecture, which serves as a critical building block in modern drug discovery and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly for oncology and targeted disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties of new chemical entities.
• Biochemical Tool Compound: Employed in vitro to study specific enzyme interactions and cellular signaling pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	4(3H)-Quinazolinone, 3-[4-(2-Chloroethoxy)Phenyl]-8-Methoxy-2-(4-Methoxyphenyl)-
CAS No.	242478-10-0
Molecular Formula	C24H21ClN2O3
Molecular Weight	420.89 g/mol
Synonyms	3-[4-(2-Chloroethoxy)phenyl]-8-methoxy-2-(4-methoxyphenyl)-4(3H)-quinazolinone; 8-Methoxy-2-(4-methoxyphenyl)-3-[4-(2-chloroethoxy)phenyl]quinazolin-4(3H)-one; 242478-10-0; Quinazolin-4(3H)-one derivative; Aryl-substituted quinazolinone.
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.