Description

2-Methyl-5H-chromeno[3,4-c]pyridine-1-carbonitrile (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities. The product is supplied as a free base, offering flexibility for downstream salt formation and derivatization processes.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct fused chromenopyridine cores, which are privileged structures in medicinal chemistry.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial labs for studying structure-activity relationships (SAR).
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents with specific biological activity.
• Material Science Exploration: Investigated for use in the synthesis of organic electronic materials due to its conjugated π-system.

Basic Information

Product Name	2-Methyl-5H-chromeno[3,4-c]pyridine-1-carbonitrile (Saltdata: Free)
CAS No.	242474-54-0
Molecular Formula	C₁₄H₁₀N₂O
Molecular Weight	222.24 g/mol
Synonyms	2-Methyl-5H-chromeno[3,4-c]pyridine-1-carbonitrile; 1-Cyano-2-methyl-5H-chromeno[3,4-c]pyridine; 242474-54-0; 2-Methyl-1-cyano-5H-chromeno[3,4-c]pyridine; Chromeno[3,4-c]pyridine-1-carbonitrile, 2-methyl-5H-; 5H-Chromeno[3,4-c]pyridine-1-carbonitrile, 2-methyl-
EINECS	Contact for details

Quality Control

Our 2-Methyl-5H-chromeno[3,4-c]pyridine-1-carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.