Description

(2S,3S,5R,6R)-5,6-Bis(Hydroxymethyl)-2,3-Dimethoxy-2,3-Dimethyl-1,4-Dioxane is a high-purity, stereochemically defined chiral building block and intermediate. This compound matters for its precise molecular architecture, which is critical for imparting specific biological activity and stereochemical control in advanced synthesis. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), complex natural products, and specialty fine chemicals where stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly for antiviral, anticancer, or antibiotic therapies.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric hydrogenation and C-C bond formation reactions.
• Glycochemistry & Carbohydrate Mimetics: Used in the research and development of glycosidase inhibitors, glycomimetic drugs, and novel carbohydrate-based materials.
• Advanced Material Science: Potential monomer or cross-linker for creating polymers with specific chiral or functional properties for specialty coatings or resins.
• Academic & Process R&D: A valuable tool for methodological studies in organic synthesis, total synthesis projects, and scaling up chiral technologies.
• Agrochemical Synthesis: Intermediate in the development of enantiomerically pure agrochemicals such as herbicides or fungicides with improved efficacy and environmental profiles.

Basic Information

Product Name	(2S,3S,5R,6R)-5,6-Bis(Hydroxymethyl)-2,3-Dimethoxy-2,3-Dimethyl-1,4-Dioxane
CAS No.	241811-66-5
Molecular Formula	C10H20O6
Molecular Weight	236.26 g/mol
Synonyms	(2S,3S,5R,6R)-2,3-Dimethoxy-2,3-dimethyl-5,6-bis(hydroxymethyl)-1,4-dioxane; (2S,3S,5R,6R)-5,6-Di(hydroxymethyl)-2,3-dimethoxy-2,3-dimethyl-1,4-dioxane; (2S,3S,5R,6R)-2,3-Dimethyl-2,3-dimethoxy-5,6-bis(hydroxymethyl)-1,4-dioxane; 1,4-Dioxane-2,3-dimethanol, 2,3-dimethoxy-2,3-dimethyl-, (2S,3S,5R,6R)-; Chiral 1,4-dioxane derivative; Tetramethylated bis-hydroxymethyl dioxane
EINECS	Contact for details

Quality Control

Our (2S,3S,5R,6R)-5,6-Bis(Hydroxymethyl)-2,3-Dimethoxy-2,3-Dimethyl-1,4-Dioxane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.