Description

1,8-Naphthyridin-2-Amine,n-(4-Chlorophenyl)-5,7-Bis(Trifluoromethyl)-(9Ci) is a high-value, fluorinated naphthyridine derivative, a sophisticated heterocyclic building block prized for its unique structural and electronic properties. Its core value proposition lies in enabling advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for medicinal chemists and material scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new molecules with enhanced bioactivity or specific physical characteristics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for targeting challenging disease pathways.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or insecticides, leveraging the biological activity of the naphthyridine core.
• Material Science: Serves as a building block for advanced organic electronic materials, such as OLEDs or semiconductors, due to the electron-withdrawing trifluoromethyl groups.
• Ligand Synthesis: Can be utilized to create complex chelating ligands for catalysis or metal-organic frameworks (MOFs).
• Fluorescent Probe Development: The rigid naphthyridine structure makes it a candidate scaffold for developing new fluorescent dyes or sensors.
• Academic & Contract Research: A critical reagent for universities and CROs conducting fundamental research in organic chemistry and medicinal chemistry.

Basic Information

Item	Detail
Product Name	1,8-Naphthyridin-2-Amine,n-(4-Chlorophenyl)-5,7-Bis(Trifluoromethyl)-(9Ci)
CAS No.	241488-35-7
Molecular Formula	C₁₇H₈ClF₆N₃
Molecular Weight	403.71 g/mol
Synonyms	N-(4-Chlorophenyl)-5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-amine; 2-Amino-N-(4-chlorophenyl)-5,7-bis(trifluoromethyl)-1,8-naphthyridine; 5,7-Bis(trifluoromethyl)-N-(4-chlorophenyl)-1,8-naphthyridin-2-amine; 1,8-Naphthyridine-2-amine, N-(4-chlorophenyl)-5,7-bis(trifluoromethyl)-; 241488-35-7; (9CI) designation
EINECS	Contact for details

Quality Control

Our production of 1,8-Naphthyridin-2-Amine,n-(4-Chlorophenyl)-5,7-Bis(Trifluoromethyl)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.