Description

1,8-Naphthyridin-2-Amine,n-Phenyl-5,7-Bis(Trifluoromethyl)-(9Ci) is a specialized heterocyclic organic compound featuring a naphthyridine core substituted with phenyl and trifluoromethyl groups. This structure is significant for its role as a key pharmaceutical intermediate and advanced building block in medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily sought by R&D chemists and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and high-performance chemical products.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in creating novel pesticides and herbicides, leveraging the biological activity of the naphthyridine scaffold.
• Material Science: Serves as a precursor for organic electronic materials and ligands in catalytic systems due to its electron-deficient aromatic system.
• Chemical Synthesis: Employed in academic and industrial research for constructing complex heterocyclic compounds for screening libraries.
• Fluorinated Compound Development: The bis(trifluoromethyl) groups make it a valuable synthon for introducing fluorine atoms to enhance metabolic stability and lipophilicity in drug design.

Basic Information

Item	Details
Product Name	1,8-Naphthyridin-2-Amine,n-Phenyl-5,7-Bis(Trifluoromethyl)-(9Ci)
CAS No.	241488-32-4
Molecular Formula	C₁₇H₉F₆N₃
Molecular Weight	369.27 g/mol
Synonyms	N-Phenyl-5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-amine; 5,7-Bis(trifluoromethyl)-N-phenyl-1,8-naphthyridin-2-amine; 2-Amino-N-phenyl-5,7-bis(trifluoromethyl)-1,8-naphthyridine; 1,8-Naphthyridine-2-amine, N-phenyl-5,7-bis(trifluoromethyl)-; 241488-32-4; 5,7-Bis(trifluoromethyl)-2-(phenylamino)-1,8-naphthyridine; N-Phenyl-5,7-bis(trifluoromethyl)[1,8]naphthyridin-2-ylamine
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridin-2-Amine,n-Phenyl-5,7-Bis(Trifluoromethyl)-(9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and full characterization data are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.