Description

1,8-Naphthyridine,7-(4-Phenyl-1-Piperazinyl)-2,4-Bis(Trifluoromethyl)-(9Ci) is a specialized heterocyclic organic compound featuring a naphthyridine core substituted with a phenylpiperazine moiety and two trifluoromethyl groups. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis due to its complex, multi-functional structure.
• Agrochemical Development: Acts as a building block for creating novel active ingredients with potential herbicidal or pesticidal properties.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Material Science Research: Investigated as a potential component for advanced organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	1,8-Naphthyridine,7-(4-Phenyl-1-Piperazinyl)-2,4-Bis(Trifluoromethyl)-(9Ci)
CAS No.	241488-25-5
Molecular Formula	C21H16F6N4
Molecular Weight	438.37 g/mol
Synonyms	7-(4-Phenylpiperazin-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine; 2,4-Bis(trifluoromethyl)-7-(4-phenyl-1-piperazinyl)-1,8-naphthyridine; 1,8-Naphthyridine, 7-(4-phenyl-1-piperazinyl)-2,4-bis(trifluoromethyl)-; 241488-25-5; 7-(4-Phenylpiperazin-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (9CI)
EINECS	Contact for details

Quality Control

Our production of 1,8-Naphthyridine,7-(4-Phenyl-1-Piperazinyl)-2,4-Bis(Trifluoromethyl)-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC purity analysis, NMR and MS structural confirmation, and residual solvent screening to ensure consistency and identity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.