Description

2-(Trifluoromethyl)-1,6-Naphthyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its naphthyridine core and trifluoromethyl substituent. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high specificity and metabolic stability. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially in oncology, antiviral, and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the biological activity of the naphthyridine scaffold.
• Material Science: Serves as a specialized monomer or additive in the creation of advanced polymers and electronic materials.
• Chemical Synthesis: Employed in organic synthesis as a versatile building block for constructing complex heterocyclic compounds in medicinal chemistry.
• Academic & R&D: Utilized in university and corporate research laboratories for method development and exploratory chemistry projects.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up and cGMP production of clinical trial materials.

Basic Information

Product Name	2-(Trifluoromethyl)-1,6-Naphthyridine-3-Carboxylic Acid
CAS No.	240408-97-3
Molecular Formula	C10H5F3N2O2
Molecular Weight	242.16 g/mol
Synonyms	2-(Trifluoromethyl)-1,6-naphthyridine-3-carboxylic acid; 1,6-Naphthyridine-3-carboxylic acid, 2-(trifluoromethyl)-; 240408-97-3; 2-Trifluoromethyl-1,6-naphthyridine-3-carboxylic acid; 3-Carboxy-2-trifluoromethyl-1,6-naphthyridine
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)-1,6-Naphthyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.