Description

5,7-Bis(Trifluoromethyl)-4-Hydroxyquinoline-3-Carboxylic Acid is a high-value, multi-functional fluorinated quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring two trifluoromethyl groups and a carboxylic acid moiety, makes it an essential building block for creating novel compounds with enhanced biological activity and material properties. This product is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, crop protection, and the development of advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity, metabolic stability, and biological activity.
• Material Science: Serves as a monomer or additive for creating specialty polymers, coatings, and electronic materials with unique thermal, chemical, or optical properties.
• Chemical Synthesis: Acts as a versatile scaffold in medicinal and combinatorial chemistry for constructing complex molecular libraries for high-throughput screening.
• Fluorine Chemistry Research: An important compound for academic and industrial research focused on understanding and applying organofluorine chemistry.

Basic Information

Item	Details
Product Name	5,7-Bis(Trifluoromethyl)-4-Hydroxyquinoline-3-Carboxylic Acid
CAS No.	240408-95-1
Molecular Formula	C₁₃H₅F₆NO₃
Molecular Weight	337.17 g/mol
Synonyms	4-Hydroxy-5,7-bis(trifluoromethyl)quinoline-3-carboxylic acid; 5,7-Bis(trifluoromethyl)-4-hydroxy-3-quinolinecarboxylic acid; 3-Quinolinecarboxylic acid, 5,7-bis(trifluoromethyl)-4-hydroxy-; 240408-95-1; 4-Hydroxy-5,7-di(trifluoromethyl)quinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5,7-Bis(Trifluoromethyl)-4-Hydroxyquinoline-3-Carboxylic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure compliance with exacting customer and research standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.