Description

2,7-Diazaspiro[4.5]Decane-7-Carboxylic Acid T-Butyl Ester is a sophisticated spirocyclic building block of significant importance in modern organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Scaffold: Used to explore structure-activity relationships (SAR) due to its constrained, three-dimensional spirocyclic structure, which can improve drug-like properties.
• Peptidomimetic Research: Employed in the design and synthesis of peptidomimetics, where it can mimic peptide turn structures or serve as a proline surrogate.
• Chemical Biology Probes: Utilized as a building block for creating tool compounds and molecular probes to study biological pathways.
• Agrochemical Synthesis: Potential intermediate in the development of novel crop protection agents with unique modes of action.
• Academic & Contract Research: Serves as a valuable reagent for academic research institutions and contract research organizations (CROs) focused on synthetic methodology and novel compound libraries.

Basic Information

Product Name	2,7-Diazaspiro[4.5]Decane-7-Carboxylic Acid T-Butyl Ester
CAS No.	236406-61-4
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	7-(tert-Butoxycarbonyl)-2,7-diazaspiro[4.5]decane; tert-Butyl 2,7-diazaspiro[4.5]decane-7-carboxylate; 2,7-Diazaspiro[4.5]decane-7-carboxylic acid, 1,1-dimethylethyl ester; 2,7-Diazaspiro[4.5]decane-7-carboxylic acid tert-butyl ester; Boc-2,7-diazaspiro[4.5]decane; 7-Boc-2,7-diazaspiro[4.5]decane; 1-tert-Butyl 7-? 2,7-diazaspiro[4.5]decane-1,7-dicarboxylate (common misassignment); Spirocyclic piperazine derivative
EINECS	Contact for details

Quality Control

Our production of 2,7-Diazaspiro[4.5]Decane-7-Carboxylic Acid T-Butyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.