Description

3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, 1,1-Dimethylethyl Ester, Hydrochloride (1:1) is a high-purity, protected spirocyclic diamine derivative used as a critical building block in advanced organic synthesis. Its unique bicyclic structure and protected amine functionality make it an essential intermediate for constructing complex molecules with specific stereochemical and pharmacological properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential central nervous system (CNS) agents and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for neurological and psychiatric disorders.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its spirocyclic scaffold for bioactivity.
• Chemical Biology & Proteomics: Serves as a scaffold or linker in the design of molecular probes, enzyme inhibitors, and activity-based probes for target identification.
• Ligand Development: Employed in medicinal chemistry for constructing complex chelating agents or receptor ligands.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and the synthesis of complex natural product analogs.
• Peptidomimetics: The spirocyclic diamine structure is valuable for designing conformationally restricted peptide mimics to enhance stability and potency.

Basic Information

Item	Details
Product Name	3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, 1,1-Dimethylethyl Ester, Hydrochloride (1:1)
CAS No.	236406-47-6
Molecular Formula	C14H27N3O2 • HCl
Molecular Weight	305.85 g/mol
Synonyms	tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate hydrochloride; 3,9-Diazaspiro[5.5]undecane-3-carboxylic acid, 1,1-dimethylethyl ester, hydrochloride; 3-(tert-Butoxycarbonyl)-3,9-diazaspiro[5.5]undecane hydrochloride; Boc-3,9-diazaspiro[5.5]undecane hydrochloride; 3,9-Diazaspiro[5.5]undecane-3-carboxylic acid tert-butyl ester hydrochloride; 3-Boc-3,9-diazaspiro[5.5]undecane HCl; Spirocyclic diamine Boc-protected hydrochloride salt
EINECS	Contact for details

Quality Control

Our production of 3,9-Diazaspiro[5.5]Undecane-3-Carboxylic Acid, 1,1-Dimethylethyl Ester, Hydrochloride (1:1) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles. We support cGMP-compliant manufacturing for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.