Description

2-Benzyl-2,8-Diaza-Spiro[4.5]Decane-8-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and diaza-bicyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, particularly within central nervous system (CNS) and other targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand and Receptor Probe Development: Employed in the design and synthesis of selective ligands for neurological and biological targets.
• Process Chemistry & Scale-Up: Serves as a defined intermediate in the optimization and commercial scale-up of synthetic routes under GMP or non-GMP conditions.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory synthetic projects and methodology development.
• Custom Synthesis & Contract Manufacturing: A specified starting material for custom synthesis projects undertaken by CDMOs (Contract Development and Manufacturing Organizations).

Basic Information

Product Name	2-Benzyl-2,8-Diaza-Spiro[4.5]Decane-8-Carboxylic Acid tert-Butyl Ester
CAS No.	236406-40-9
Molecular Formula	C20H30N2O2
Molecular Weight	330.47 g/mol
Synonyms	tert-Butyl 2-benzyl-2,8-diazaspiro[4.5]decane-8-carboxylate; 2,8-Diaza-spiro[4.5]decane-8-carboxylic acid, 2-benzyl-, 1,1-dimethylethyl ester; 2-Benzyl-2,8-diazaspiro[4.5]decane-8-carboxylic acid tert-butyl ester; 8-Boc-2-benzyl-2,8-diazaspiro[4.5]decane; 2-Benzyl-2,8-diaza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester.
EINECS	Contact for details

Quality Control

Our 2-Benzyl-2,8-Diaza-Spiro[4.5]Decane-8-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC, NMR, and MS, are validated to provide reliable specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.