Description

2-Hydroxy-5-Methyl-Phenyl-Hydrazine is a specialized aromatic hydrazine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for constructing complex heterocyclic structures, particularly in the development of active pharmaceutical ingredients (APIs) and high-performance dyes. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and specialty chemical production, where it serves as a key precursor for coupling and cyclization reactions.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various heterocyclic compounds, including pyrazoles and indazoles, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and plant growth regulators, leveraging its reactivity to form nitrogen-containing bioactive molecules.
• Dye and Pigment Manufacturing: Serves as a key coupling agent in the production of azo dyes and high-performance organic pigments, contributing to color strength and fastness.
• Chemical Research & Development: Employed as a versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
• Polymer Chemistry: Can be utilized as a monomer or modifying agent in the synthesis of specialty polymers with tailored properties.
• Analytical Chemistry: Acts as a derivatization agent for the detection and quantification of carbonyl compounds (aldehydes and ketones) in various matrices.

Basic Information

Product Name	2-Hydroxy-5-Methyl-Phenyl-Hydrazine
CAS No.	235759-30-5
Molecular Formula	C7H10N2O
Molecular Weight	138.17 g/mol
Synonyms	5-Methyl-2-hydroxyphenylhydrazine; (5-Methyl-2-hydroxyphenyl)hydrazine; 2-Hydrazinyl-4-methylphenol; 1-(5-Methyl-2-hydroxyphenyl)hydrazine; 2-Hydroxy-5-methylphenylhydrazine; 5-Methylsalicylhydrazide (common name); o-Hydroxy-p-tolylhydrazine
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-Methyl-Phenyl-Hydrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.