Description

4-Chloro-5,7-Bis(trifluoromethyl)quinoline is a high-value, multi-functional fluorinated heterocyclic building block. This compound matters for its unique combination of a quinoline core with chlorine and trifluoromethyl substituents, which imparts significant electronic and steric properties critical for advanced material and pharmaceutical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Ligand and Catalyst Development: The quinoline structure makes it suitable for designing novel ligands for metal catalysis in fine chemical synthesis.
• Fluorinated Liquid Crystal Research: Used in the development of new fluorinated components for display technologies.
• Academic and Industrial R&D: A versatile reagent for exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	4-Chloro-5,7-Bis(trifluoromethyl)quinoline
CAS No.	234450-34-1
Molecular Formula	C11H4ClF6N
Molecular Weight	299.60 g/mol
Synonyms	4-Chloro-5,7-bis(trifluoromethyl)quinoline; 5,7-Bis(trifluoromethyl)-4-chloroquinoline; 4-Chloro-5,7-di(trifluoromethyl)quinoline; Quinoline, 4-chloro-5,7-bis(trifluoromethyl)-; 234450-34-1; 4-Chloro-5,7-bis(trifluoromethyl)chinolin (German); 4-クロロ-5,7-ビス(トリフルオロメチル)キノリン (Japanese)
EINECS	Contact for details

Quality Control

Our 4-Chloro-5,7-Bis(trifluoromethyl)quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.