Description

7-Bromomethyl-4-Chloro-Quinazoline is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its dual reactive sites, the bromomethyl and chloro groups, which allow for selective and sequential functionalization to construct complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of targeted quinazoline-based active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other targeted cancer therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides with quinazoline cores.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study enzyme function and signal transduction pathways.
• Material Science Research: Employed in the synthesis of organic semiconductors and luminescent materials due to the quinazoline moiety's electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring selective alkylation or further heterocyclic elaboration.

Basic Information

Product Name	7-Bromomethyl-4-Chloro-Quinazoline
CAS No.	234098-35-2
Molecular Formula	C9H6BrClN2
Molecular Weight	257.51 g/mol
Synonyms	4-Chloro-7-(bromomethyl)quinazoline; 7-(Bromomethyl)-4-chloroquinazoline; 4-Chloro-7-bromomethylquinazoline; Quinazoline, 4-chloro-7-(bromomethyl)-; 234098-35-2; 4-Chloro-7-bromomethyl-quinazoline
EINECS	Contact for details

Quality Control

Every batch of 7-Bromomethyl-4-Chloro-Quinazoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A detailed Certificate of Analysis (COA) including results for identity, purity, and impurity profile by HPLC is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.