Description

3-Bromo-3,3-Difluoropropylamine Hydrochloride is a versatile organofluorine building block of significant interest in advanced synthetic chemistry. Its value lies in the strategic incorporation of bromine and fluorine atoms, which serve as key handles for further functionalization and to modulate the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated analogs of bioactive molecules, potentially enhancing metabolic stability, lipophilicity, and membrane permeability.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides where fluorine atoms can improve efficacy and environmental profile.
• Material Science Precursor: Serves as a starting material for synthesizing specialized fluorinated polymers, coatings, or liquid crystals with unique properties.
• Cross-Coupling Reactions: The bromine moiety acts as an excellent leaving group in palladium-catalyzed reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Nucleophilic Substitution: The amine hydrochloride salt facilitates further derivatization to amides, sulfonamides, or ureas, expanding the chemical space.
• Fluorine Chemistry Research: An essential reagent for academic and industrial labs exploring the effects of gem-difluoromethylene groups in molecular design.

Basic Information

Item	Details
Product Name	3-Bromo-3,3-Difluoropropylamine Hydrochloride
CAS No.	234096-29-8
Molecular Formula	C3H7BrClF2N
Molecular Weight	210.45 g/mol
Synonyms	3-Bromo-3,3-difluoropropan-1-amine hydrochloride; 1-Amino-3-bromo-3,3-difluoropropane hydrochloride; 3-Bromo-3,3-difluoropropylamine HCl; 3,3-Difluoro-3-bromopropylamine hydrochloride; (3-Bromo-3,3-difluoropropyl)amine hydrochloride; 234096-29-8; 3-Bromo-3,3-difluoropropanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Bromo-3,3-Difluoropropylamine Hydrochloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics is provided and available upon request, supporting your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.