Description

3-[(tert-Butoxycarbonyl)Amino]-5-Hydroxybenzoic Acid CAS NO 232595-59-4 is a high-purity, protected amino acid derivative featuring both a carboxylic acid and a phenolic hydroxyl group, making it a versatile building block for complex organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in peptide mimetics, linker chemistry, and as a key intermediate in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly for creating peptide-based therapeutics and enzyme inhibitors.
• Peptide & Linker Chemistry: Used in solid-phase peptide synthesis (SPPS) and for constructing cleavable linkers in antibody-drug conjugates (ADCs) and prodrugs.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides and plant growth regulators with specific targeting properties.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic frameworks for specialized applications.
• Bioconjugation: Utilized for modifying biomolecules, proteins, and surfaces due to its reactive carboxylic acid and protected amine functionalities.
• Chemical Biology Probes: Acts as a core structure for developing fluorescent tags, affinity labels, and other molecular probes for biological research.

Basic Information

Product Name	3-[(tert-Butoxycarbonyl)Amino]-5-Hydroxybenzoic Acid
CAS No.	232595-59-4
Molecular Formula	C12H15NO5
Molecular Weight	253.25 g/mol
Synonyms	5-Hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic acid; 3-(Boc-amino)-5-hydroxybenzoic acid; 3-((tert-Butoxycarbonyl)amino)-5-hydroxybenzoic acid; Boc-3-Amino-5-hydroxybenzoic acid; 3-Amino-5-hydroxybenzoic acid tert-butyl carbamate; 3-Boc-amino-5-hydroxybenzoic acid; 232595-59-4; tert-Butyl (3-carboxy-5-hydroxyphenyl)carbamate
EINECS	Contact for details

Quality Control

Every batch of 3-[(tert-Butoxycarbonyl)Amino]-5-Hydroxybenzoic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.