Description

Boc-3-Amino-4-Methylbenzoic Acid is a high-purity, protected benzoic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in medicinal chemistry, enabling the controlled introduction of functionalized aromatic systems. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Peptide Mimetics & Conjugation: Used to incorporate modified benzoic acid moieties into peptide backbones or for bioconjugation strategies.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for the amine functionality during multi-step syntheses.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis.
• Material Science Research: Employed in the development of organic semiconductors and advanced polymeric materials with specific functional properties.
• Agrochemical Synthesis: Acts as an intermediate in the production of advanced herbicides and plant growth regulators.

Basic Information

Product Name	Boc-3-Amino-4-Methylbenzoic Acid
CAS No.	231958-04-6
Molecular Formula	C13H17NO4
Molecular Weight	251.28 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-4-methylbenzoic Acid; 4-Methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic Acid; tert-Butyl (3-carboxy-4-methylphenyl)carbamate; Boc-3-Amino-p-toluic Acid; BOC-AMBA; N-Boc-3-amino-4-methylbenzoic acid; N-(tert-Butoxycarbonyl)-3-amino-4-methylbenzoic Acid
EINECS	Contact for details

Quality Control

Our Boc-3-Amino-4-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.