Description

2,3,4,5-Tetrahydro-7,8-Dinitro-3-(Trifluoroacetyl)-1,5-Methano-1H-3-Benzazepine is a high-purity, specialized organic compound with a complex bridged benzazepine structure, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique molecular architecture, featuring nitro and trifluoroacetyl functional groups, makes it an invaluable building block for constructing novel pharmacologically active molecules. This compound is primarily sought by research institutions and pharmaceutical development companies engaged in the synthesis of new chemical entities for neurological and psychiatric disorder research.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel benzazepine-based drug candidates targeting central nervous system (CNS) receptors.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to explore new therapeutic avenues in academic and industrial R&D labs.
• Chemical Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) campaigns in drug discovery.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Process Chemistry Development: Utilized for optimizing synthetic routes and scaling up production of complex heterocyclic compounds.

Basic Information

Item	Details
Product Name	2,3,4,5-Tetrahydro-7,8-Dinitro-3-(Trifluoroacetyl)-1,5-Methano-1H-3-Benzazepine
CAS No.	230615-59-5
Molecular Formula	C₁₄H₁₂F₃N₃O₅
Molecular Weight	359.26 g/mol
Synonyms	7,8-Dinitro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine; 1,5-Methano-1H-3-benzazepine, 2,3,4,5-tetrahydro-7,8-dinitro-3-(trifluoroacetyl)-; 230615-59-5; 3-(Trifluoroacetyl)-7,8-dinitro-1,5-methano-1H-3-benzazepine; Tetrahydro-dinitro-trifluoroacetyl-methano-benzazepine; DN-TFA-MBA intermediate; Benzazepine nitro trifluoroacetyl derivative
EINECS	Contact for details

Quality Control

Every batch of 2,3,4,5-Tetrahydro-7,8-Dinitro-3-(Trifluoroacetyl)-1,5-Methano-1H-3-Benzazepine is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.