Description

1,5-Methano-1H-3-Benzazepine, 2,3,4,5-Tetrahydro-3-(Phenylmethyl)- is a complex, high-purity benzazepine derivative, a key structural motif in advanced pharmaceutical research and development. This compound matters as a sophisticated chemical building block for synthesizing novel active pharmaceutical ingredients (APIs) and exploring new therapeutic pathways. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of central nervous system (CNS) and other specialized therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates targeting neurological receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for new chemical entities (NCEs).
• Academic Research: Utilized in university and institutional labs for studying benzazepine chemistry and pharmacology.
• Contract Research Organizations (CROs): Supplied to CROs conducting custom synthesis and preclinical studies for client projects.

Basic Information

Product Name	1,5-Methano-1H-3-Benzazepine, 2,3,4,5-Tetrahydro-3-(Phenylmethyl)-
CAS No.	230615-48-2
Molecular Formula	C19H21N
Molecular Weight	263.38 g/mol
Synonyms	3-Benzyl-2,3,4,5-tetrahydro-1,5-methano-1H-3-benzazepine; 3-(Phenylmethyl)-2,3,4,5-tetrahydro-1,5-methano-1H-3-benzazepine; 1,5-Methano-1H-3-benzazepine, 2,3,4,5-tetrahydro-3-(phenylmethyl)-; 3-Benzyl-1,5-methano-1H-3-benzazepine; Tetrahydro-3-(phenylmethyl)-1,5-methano-1H-3-benzazepine; 230615-48-2; Benzazepine derivative 230615-48-2
EINECS	Contact for details

Quality Control

Our 1,5-Methano-1H-3-Benzazepine derivative is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.