Description

(1R,5R,7S,8S)-7-(Acetyloxy)-8-(Phenylmethoxy)-3,6-Dioxabicyclo[3.2.1]Octane-5-Methanol 5-Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its complex bicyclic acetal structure. This compound is of significant commercial value for its role as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing novel therapeutics, particularly in antiviral and carbohydrate-based drug discovery.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex nucleoside analogs and other carbohydrate-based active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Serves as a key precursor in the development of novel antiviral compounds, leveraging its protected sugar-like scaffold.
• Organic Synthesis Building Block: Used in advanced asymmetric synthesis for constructing complex molecular architectures with precise stereochemistry.
• Process Chemistry & Scale-Up: Employed in route development and optimization for the commercial manufacturing of target molecules.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new chemical entities and reaction methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring high stereochemical purity.

Basic Information

Item	Details
Product Name	(1R,5R,7S,8S)-7-(Acetyloxy)-8-(Phenylmethoxy)-3,6-Dioxabicyclo[3.2.1]Octane-5-Methanol 5-Acetate
CAS No.	229469-37-8
Molecular Formula	C19H24O8
Molecular Weight	380.39 g/mol
Synonyms	1,4-Anhydro-2,3-O-benzylidene-5-O-acetyl-D-ribitol 1-Acetate; (1R,5R,7S,8S)-7-(Acetyloxy)-8-(Phenylmethoxy)-3,6-Dioxabicyclo[3.2.1]octane-5-methanol 5-acetate; 2,3-O-Benzylidene-5-O-acetyl-1,4-anhydro-D-ribitol 1-acetate; Bicyclic D-ribitol derivative acetate; CAS 229469-37-8
EINECS	Contact for details

Quality Control

Our (1R,5R,7S,8S)-7-(Acetyloxy)-8-(Phenylmethoxy)-3,6-Dioxabicyclo[3.2.1]Octane-5-Methanol 5-Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.