Description

(3R)-3-Aminomethyl-1-Benzylpyrrolidine CAS NO 229323-04-0 is a chiral, nitrogen-containing heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its value lies in its well-defined stereochemistry and functional groups, which make it an essential intermediate for constructing complex molecules with high biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, especially in neurological and psychiatric disorders.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for stereoselective reactions.
• Medicinal Chemistry Research: A versatile scaffold for constructing focused libraries in structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Intermediate in the production of advanced, chiral crop protection agents and pesticides.
• Chemical Biology Probes: Building block for creating molecular probes to study enzyme function and biological pathways.
• Peptidomimetics: Core structure for designing peptide analogs with enhanced stability and bioavailability.

Basic Information

Product Name	(3R)-3-Aminomethyl-1-Benzylpyrrolidine
CAS No.	229323-04-0
Molecular Formula	C12H18N2
Molecular Weight	190.29 g/mol
Synonyms	(R)-1-Benzyl-3-(aminomethyl)pyrrolidine; (3R)-1-Benzyl-3-(aminomethyl)pyrrolidine; (R)-3-Aminomethyl-1-benzylpyrrolidine; 1-Benzyl-(3R)-3-(aminomethyl)pyrrolidine; (R)-1-Benzyl-3-pyrrolidinemethanamine; (R)-N-Benzyl-3-(aminomethyl)pyrrolidine; (R)-ABP; (R)-BAMP
EINECS	Contact for details

Quality Control

Our (3R)-3-Aminomethyl-1-Benzylpyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.