Description

13-Oxo-1,4,7,10-Tetraazabicyclo[8.2.1]Tridecane-4,7-Diacetic Acid is a high-purity, advanced bifunctional chelating agent and a key intermediate in the synthesis of sophisticated macrocyclic compounds. Its core value lies in its ability to form exceptionally stable complexes with a range of metal ions, which is critical for applications demanding high specificity and low background interference. This product is essential for researchers and manufacturers in the pharmaceutical, diagnostic imaging, and advanced materials sectors who require reliable, high-quality building blocks for complex ligand systems.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel macrocyclic ligands for therapeutic radiopharmaceuticals and MRI contrast agents.
• Diagnostic Imaging: Used to create chelators that bind diagnostic radionuclides (e.g., 68Ga, 177Lu, 99mTc) for targeted Positron Emission Tomography (PET) and Single-Photon Emission Computed Tomography (SPECT).
• Catalysis Research: Serves as a scaffold for developing highly selective and efficient metal-based catalysts for organic synthesis.
• Chemical Biology Probes: Enables the creation of metal-chelating tags for labeling proteins, antibodies, and other biomolecules for detection and purification.
• Advanced Material Synthesis: A building block for metal-organic frameworks (MOFs) and other functional materials with tailored properties.
• Analytical Chemistry: Used in the development of selective chelating resins and sensors for metal ion detection and separation.

Basic Information

Product Name	13-Oxo-1,4,7,10-Tetraazabicyclo[8.2.1]Tridecane-4,7-Diacetic Acid
CAS No.	229312-33-8
Molecular Formula	C13H22N4O5
Molecular Weight	314.34 g/mol
Synonyms	1,4,7,10-Tetraazabicyclo[8.2.1]tridecane-4,7-diacetic acid, 13-oxo-; DO2A-ON; 13-Oxo-DO2A; 13-Oxo-1,4,7,10-tetraazabicyclo[8.2.1]tridecane-4,7-diacetic acid; 13-Oxo-DO2A chelator; 13-Keto-DO2A; (4,7-Bis(carboxymethyl)-13-oxo-1,4,7,10-tetraazabicyclo[8.2.1]tridecan-10-yl)acetic acid
EINECS	Contact for details

Quality Control

Our 13-Oxo-1,4,7,10-Tetraazabicyclo[8.2.1]Tridecane-4,7-Diacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports applications in regulated environments, including pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.