Description

N1-Fmoc-N2-Methyl-1,2-Ethandiamine Hcl is a protected diamine derivative, specifically engineered for advanced organic synthesis and peptide chemistry. This compound serves as a crucial key building block for introducing a methyl-substituted ethylenediamine moiety into complex molecular architectures under Fmoc-protection strategies. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), peptide-based therapeutics, and specialized chemical libraries.

Application

• Peptide Synthesis: As a key intermediate for incorporating modified ethylenediamine structures into peptide chains using solid-phase or solution-phase Fmoc chemistry.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes, linkers, and conjugates for studying biological processes and protein interactions.
• Ligand and Catalyst Development: Acts as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Bioconjugation: Facilitates the site-specific modification of biomolecules, such as proteins and antibodies, for diagnostic and therapeutic applications.
• Material Science: Employed in the synthesis of functional polymers and dendrimers with tailored amine functionalities.

Basic Information

Product Name	N1-Fmoc-N2-Methyl-1,2-Ethandiamine Hcl
CAS No.	229028-44-8
Molecular Formula	C₁₉H₂₃N₂O₂•HCl
Molecular Weight	356.86 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-methylethane-1,2-diamine hydrochloride; Fmoc-N-Me-ethylenediamine hydrochloride; 1-[(9-Fluorenylmethyloxycarbonyl)amino]-2-(methylamino)ethane hydrochloride; Nα-Fmoc-Nβ-methyl-1,2-diaminoethane hydrochloride; N-Fmoc-N'-methylethylenediamine HCl; (2-{[(9H-Fluoren-9-ylmethoxy)carbonyl](methyl)amino}ethyl)amine hydrochloride; Fmoc-MeEDA•HCl
EINECS	Contact for details

Quality Control

Our N1-Fmoc-N2-Methyl-1,2-Ethandiamine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.