Description

5,7-Difluoro-4-Hydroxyquinoline-3-Carboxylic Acid Ethyl Ester is a high-value fluorinated quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological or material properties. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated quinolone antibiotics and other therapeutic agents.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Organic Synthesis: Serves as a versatile precursor for synthesizing more complex heterocyclic compounds, ligands, and functional materials in academic and industrial R&D.
• Material Science: Potential use in the development of organic semiconductors, fluorescent dyes, or metal-organic frameworks (MOFs) due to its conjugated quinoline structure.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	5,7-Difluoro-4-Hydroxyquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	228728-82-3
Molecular Formula	C₁₂H₉F₂NO₃
Molecular Weight	253.20 g/mol
Synonyms	Ethyl 5,7-Difluoro-4-hydroxyquinoline-3-carboxylate; 4-Hydroxy-5,7-difluoroquinoline-3-carboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 5,7-difluoro-4-hydroxy-, ethyl ester; 5,7-Difluoro-4-hydroxy-3-quinolinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-4-Hydroxyquinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.