Description

6-tert-Butyl-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, synthetically derived quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, offering a unique structural motif for pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its quinoline core for biological activity.
• Material Science Research: Serves as a monomer or functional additive in the development of advanced polymers and organic electronic materials.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized quinoline-based dyes and colorants for technical applications.

Basic Information

Product Name	6-tert-Butyl-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	228728-32-3
Molecular Formula	C₁₇H₂₁NO₃
Molecular Weight	287.35 g/mol
Synonyms	Ethyl 6-tert-butyl-4-hydroxyquinoline-3-carboxylate; 4-Hydroxy-6-tert-butylquinoline-3-carboxylic acid ethyl ester; 6-tert-Butyl-4-hydroxy-3-quinolinecarboxylic acid ethyl ester; 6-(tert-Butyl)-4-hydroxyquinoline-3-carboxylic acid ethyl ester; 228728-32-3; Quinoline-3-carboxylic acid, 6-(1,1-dimethylethyl)-4-hydroxy-, ethyl ester; Ethyl 6-(tert-butyl)-4-oxo-1,4-dihydroquinoline-3-carboxylate (tautomeric form)
EINECS	Contact for details

Quality Control

Our 6-tert-Butyl-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.