Description

6,8-Difluoro-4-Hydroxyquinoline-3-Carboxylic Acid is a high-purity fluorinated quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antibiotic and antibacterial agents, particularly fluoroquinolone-class drugs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the fluorine atoms for improved efficacy and environmental stability.
• Chemical Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal and materials chemistry.
• Biochemical Research: Employed as a standard or reagent in studies targeting bacterial enzymes like DNA gyrase and topoisomerase IV.
• Material Science: Potential intermediate for the synthesis of organic electronic materials or fluorescent markers due to the quinoline core structure.

Basic Information

Product Name	6,8-Difluoro-4-Hydroxyquinoline-3-Carboxylic Acid
CAS No.	228728-19-6
Molecular Formula	C10H5F2NO3
Molecular Weight	225.15 g/mol
Synonyms	4-Hydroxy-6,8-difluoroquinoline-3-carboxylic acid; 6,8-Difluoro-4-hydroxy-3-quinolinecarboxylic acid; 3-Quinolinecarboxylic acid, 6,8-difluoro-4-hydroxy-; 6,8-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 6,8-Difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid; DFHQCA; 228728-19-6 (CAS)
EINECS	Contact for details

Quality Control

Our 6,8-Difluoro-4-Hydroxyquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. We provide material with typical purity levels ≥98% (HPLC), tailored to meet the stringent requirements of pharmaceutical R&D and production. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, ensuring traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.