Description

5,7-Difluoro-4-Hydroxy-Quinoline-3-Carboxylic Acid is a high-purity fluorinated quinoline derivative serving as a critical advanced pharmaceutical intermediate. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in antimicrobial and anticancer research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides leveraging the fluorinated quinoline scaffold.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for creating complex heterocyclic compounds.
• Material Science: Potential use in the development of specialty chemicals and functional materials.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5,7-Difluoro-4-Hydroxy-Quinoline-3-Carboxylic Acid
CAS No.	228728-18-5
Molecular Formula	C10H5F2NO3
Molecular Weight	225.15 g/mol
Synonyms	4-Hydroxy-5,7-difluoroquinoline-3-carboxylic acid; 5,7-Difluoro-4-hydroxy-3-quinolinecarboxylic acid; 3-Quinolinecarboxylic acid, 5,7-difluoro-4-hydroxy-; DFHQCA; 228728-18-5; 5,7-Difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-4-Hydroxy-Quinoline-3-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.