Description

Cyclopentanecarboxylic Acid, 2-(Hydroxymethyl)-, Hydrazide, (1S,2R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of a cyclopentane backbone, a hydroxymethyl group, and a reactive hydrazide functionality, enabling its use in constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the construction of novel, stereospecific herbicides, fungicides, and plant growth regulators where specific spatial orientation is critical for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity in chemical reactions.
• Peptidomimetic Research: The hydrazide group and constrained cyclopentane ring make it valuable for designing and synthesizing peptide mimics with enhanced metabolic stability and bioavailability.
• Material Science: Potential building block for specialty polymers and dendrimers requiring precise molecular geometry and functional group density.
• Academic & Contract Research: Essential for fundamental organic chemistry research and for contract research organizations (CROs) working on custom synthesis projects for clients.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-(Hydroxymethyl)-, Hydrazide, (1S,2R)- (9Ci)
CAS No.	228422-22-8
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	(1S,2R)-2-(Hydroxymethyl)cyclopentanecarboxylic acid hydrazide; (1S,2R)-2-(Hydroxymethyl)cyclopentane-1-carbohydrazide; (1S,2R)-2-Hydroxymethylcyclopentanecarboxylic acid hydrazide; (1S,2R)-rel-2-(Hydroxymethyl)cyclopentanecarbohydrazide; (1S,2R)-2-(Hydroxymethyl)-1-cyclopentanecarbohydrazide; (1S,2R)-2-(Hydroxymethyl)cyclopentane-1-carboxylic acid hydrazide; Cyclopentanecarboxylic acid, 2-(hydroxymethyl)-, hydrazide, (1S,2R)-rel-
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-(Hydroxymethyl)-, Hydrazide, (1S,2R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.