Description

(S)-1,2-Dihydroacenaphthylen-1-Amine is a high-purity chiral amine building block of significant interest in advanced organic synthesis. Its rigid, fused polycyclic structure and defined stereochemistry make it a valuable precursor for constructing complex molecules with specific three-dimensional architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-cancer therapies.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize novel chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Synthesis: Employed as a building block for creating chiral active ingredients in advanced pesticides and herbicides.
• Material Science Research: Investigated for the synthesis of chiral organic semiconductors, liquid crystals, or functional polymers.
• Academic & Process Chemistry: Utilized in methodological studies and scale-up process development for stereoselective synthesis.

Basic Information

Product Name	(S)-1,2-Dihydroacenaphthylen-1-Amine
CAS No.	228246-74-0
Molecular Formula	C12H11N
Molecular Weight	169.22 g/mol
Synonyms	(1S)-1,2-Dihydroacenaphthylen-1-amine; (S)-1-Amino-1,2-dihydroacenaphthylene; (S)-1,2-Dihydroacenaphthylene-1-amine; (S)-1-Aminoacenaphthene; (S)-Acenaphthen-1-amine; (1S)-Acenaphthylen-1-amine; (S)-1-Acenaphthenylamine
EINECS	Contact for details

Quality Control

Our (S)-1,2-Dihydroacenaphthylen-1-Amine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity determination by HPLC, to ensure consistent high quality and enantiomeric excess (ee). A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and related substances is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.