Description

tert-Butyl 3-(1,5,6,7-Tetrahydro-1,8-naphthyridin-2-yl)propylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused bicyclic structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of complex bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents, particularly within the fields of neurology and oncology.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Neurological Drug Development: Serves as a key structural component in the research of compounds targeting central nervous system (CNS) disorders.
• Oncological Agent Synthesis: Employed in the construction of potential kinase inhibitors and other anti-cancer candidate molecules.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying specific biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific novel chemical entities (NCEs).

Basic Information

Product Name	tert-Butyl 3-(1,5,6,7-Tetrahydro-1,8-naphthyridin-2-yl)propylcarbamate
CAS No.	227751-86-2
Molecular Formula	C16H25N3O2
Molecular Weight	291.39 g/mol
Synonyms	Boc-3-(1,5,6,7-Tetrahydro-1,8-naphthyridin-2-yl)propylamine; tert-Butyl N-[3-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)propyl]carbamate; 2-(3-((tert-Butoxycarbonyl)amino)propyl)-1,5,6,7-tetrahydro-1,8-naphthyridine; 227751-86-2; 1,8-Naphthyridine, 1,2,3,4-tetrahydro-2-[3-[[(1,1-dimethylethoxy)carbonyl]amino]propyl]-; Boc-1,8-naphthyridine propylamine derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(1,5,6,7-Tetrahydro-1,8-naphthyridin-2-yl)propylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.