Description

Methyl 5-(5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Yl)Pentanoate CAS NO 227751-47-5 is a high-purity, advanced pharmaceutical intermediate characterized by its naphthyridine core structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Integral building block for constructing the core structure of potential new chemical entities (NCEs) in preclinical development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of clinical trial materials.
• Biochemical Research: Employed in the development of enzyme inhibitors or receptor modulators due to its heterocyclic structure.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Methyl 5-(5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Yl)Pentanoate
CAS No.	227751-47-5
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	Methyl 5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)valerate; 5-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)pentanoic acid methyl ester; 2-(5-Methoxy-5-oxopentyl)-5,6,7,8-tetrahydro-1,8-naphthyridine; Methyl 5-(1,2,3,4-tetrahydro-1,8-naphthyridin-2-yl)pentanoate (tautomeric form); 227751-47-5; THN-Pentanoate Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 5-(5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Yl)Pentanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive compound.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.