Description

Cyclohexanamine, 3-Methyl-5-(1-Methylethyl)-, (1R,3R,5S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral amine building block of significant interest in advanced organic synthesis. Its rigid cyclohexyl backbone and specific isopropyl substitution pattern make it a valuable scaffold for constructing complex molecules with defined three-dimensional architecture. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its chiral purity is critical for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the stereochemistry influences efficacy and environmental profile.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis, enabling enantioselective transformations.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for producing specialty chemicals, flavors, and fragrances.
• Academic & Industrial Research: A valuable tool compound in medicinal chemistry and material science research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Cyclohexanamine, 3-Methyl-5-(1-Methylethyl)-, (1R,3R,5S)-Rel- (9Ci)
CAS No.	226548-58-9
Molecular Formula	C10H21N
Molecular Weight	155.28 g/mol
Synonyms	(1R,3R,5S)-3-Methyl-5-(propan-2-yl)cyclohexan-1-amine; (1R,3R,5S)-3-Methyl-5-isopropylcyclohexylamine; (1R,3R,5S)-1-Amino-3-methyl-5-isopropylcyclohexane; rel-(1R,3R,5S)-3-Methyl-5-(1-methylethyl)cyclohexanamine; 3-Methyl-5-isopropylcyclohexylamine (stereoisomer); Chiral Isopropylmethylcyclohexylamine; Stereoisomer of Menthylamine derivative
EINECS	Contact for details

Quality Control

Our production of Cyclohexanamine, 3-Methyl-5-(1-Methylethyl)-, (1R,3R,5S)-Rel- (9Ci) adheres to stringent quality control protocols to ensure batch-to-batch consistency and high chiral purity, which is essential for sensitive synthetic applications. All materials are characterized using advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.