Description

2-[(4S)-4-(1,1-Dimethylethyl)-4,5- Dihydro-2-Oxazolyl]-Quinoline is a high-value, chiral oxazoline-quinoline hybrid compound that serves as a critical building block in advanced organic synthesis. Its unique structure makes it an essential ligand precursor and intermediate for developing novel pharmaceuticals and specialty chemicals. This compound is primarily sought after by research institutions and industrial R&D departments focused on catalysis, medicinal chemistry, and the synthesis of complex molecules.

Application

• Asymmetric Catalysis: Acts as a precursor for chiral oxazoline ligands used in enantioselective synthesis, including hydrogenation and cyclopropanation reactions.
• Pharmaceutical Intermediates: Serves as a key building block in the research and development of active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Material Science Research: Utilized in the development of novel organic electronic materials and luminescent compounds due to the quinoline moiety.
• Agrochemical Synthesis: Employed as an intermediate in the creation of advanced, high-performance crop protection agents.
• Academic & Industrial R&D: A valuable tool compound for method development and exploring new reaction pathways in organic chemistry.

Basic Information

Product Name	2-[(4S)-4-(1,1-Dimethylethyl)-4,5- Dihydro-2-Oxazolyl]-Quinoline
CAS No.	226387-12-8
Molecular Formula	C₁₆H₁₈N₂O
Molecular Weight	254.33 g/mol
Synonyms	(4S)-4-(tert-Butyl)-4,5-dihydro-2-(quinolin-2-yl)oxazole; (S)-4-(tert-Butyl)-2-(quinolin-2-yl)-4,5-dihydrooxazole; 2-[(4S)-4-(tert-Butyl)-4,5-dihydrooxazol-2-yl]quinoline; (S)-2-(2-Quinolyl)-4-tert-butyl-2-oxazoline; Quinoline, 2-[(4S)-4-(1,1-dimethylethyl)-4,5-dihydro-2-oxazolyl]-; (S)-t-Bu-Quinox Ligand Precursor
EINECS	Contact for details

Quality Control

Every batch of 2-[(4S)-4-(1,1-Dimethylethyl)-4,5- Dihydro-2-Oxazolyl]-Quinoline is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high chiral purity and chemical integrity to meet the exacting standards of research and process development. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess, and identification data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.