Description

(S)-2-(4,5-Dihydro-4-Isopropyl-2-Oxazolyl)Quinoline is a high-purity chiral oxazoline derivative, a crucial building block in asymmetric synthesis and pharmaceutical research. Its value lies in its role as a versatile ligand precursor and organocatalyst, enabling the production of enantiomerically pure compounds with high stereoselectivity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require advanced intermediates for developing new active ingredients and specialty materials.

Application

• Asymmetric Catalysis: Serves as a precursor for chiral oxazoline ligands used in transition metal-catalyzed reactions such as asymmetric hydrogenation, cyclopropanation, and Diels-Alder reactions.
• Pharmaceutical Intermediates: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the development of chiral polymers, liquid crystals, and advanced organic materials with specific optical properties.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate labs exploring new methodologies in stereoselective synthesis.

Basic Information

Product Name	(S)-2-(4,5-Dihydro-4-Isopropyl-2-Oxazolyl)Quinoline
CAS No.	226387-11-7
Molecular Formula	C₁₅H₁₆N₂O
Molecular Weight	240.30 g/mol
Synonyms	(S)-2-(4,5-Dihydro-4-isopropyl-2-oxazolyl)quinoline; (S)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)quinoline; (S)-4-Isopropyl-2-(quinolin-2-yl)-4,5-dihydrooxazole; (S)-Quinox; (S)-Quinoline-oxazoline ligand precursor; (S)-2-(2-Quinolyl)-4-isopropyl-4,5-dihydrooxazole; (S)-iPr-Quinox
EINECS	Contact for details

Quality Control

Our (S)-2-(4,5-Dihydro-4-Isopropyl-2-Oxazolyl)Quinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.