Description

2-Naphthalenemethanol, α-(1-Chloroethylidene)-, (Alphaz)- (9Ci) is a specialized organic intermediate of significant interest in advanced synthetic chemistry. Its unique molecular architecture, featuring a naphthalene backbone with chlorinated and hydroxylated functional groups, makes it a valuable building block for constructing complex molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical sectors. It serves as a critical precursor in the synthesis of novel active ingredients and fine chemicals requiring specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, or plant growth regulators where the naphthalene structure imparts specific biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, or organic electronic materials.
• Catalyst Ligand Preparation: The functional groups can be modified to create chiral ligands for asymmetric catalysis in fine chemical production.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry optimization studies in academic and industrial laboratories.

Basic Information

Product Name	2-Naphthalenemethanol, α-(1-Chloroethylidene)-, (Alphaz)- (9Ci)
CAS No.	224953-69-9
Molecular Formula	C₁₃H₁₁ClO
Molecular Weight	218.68 g/mol
Synonyms	α-(1-Chloroethylidene)-2-naphthalenemethanol; (αZ)-α-(1-Chloroethylidene)-2-naphthalenemethanol; 2-Naphthalenemethanol, α-(1-chloroethylidene)-, (αZ)-; (Z)-α-(1-Chloroethylidene)-2-naphthalenemethanol; (Alphaz)-2-Naphthalenemethanol, α-(1-Chloroethylidene)-; 1-(1-Chloroethylidene)-2-(hydroxymethyl)naphthalene (Z)-isomer
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for this advanced intermediate. Our production adheres to strict internal specifications, with quality verified by modern analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of reactive functional groups, it should be stored separately from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.