Description

4-Bromo-5-Fluoro-2-Nitrotoluene is a high-purity halogenated nitrotoluene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a multifunctional aromatic core with strategically placed bromo, fluoro, and nitro substituents, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides where the fluorine and bromine atoms enhance biological activity and stability.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing complex halogenated dyes and colorants.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Nucleophilic Aromatic Substitution: The activated nitro and fluoro groups allow for selective substitution, enabling diverse functionalization.

Basic Information

Product Name	4-Bromo-5-Fluoro-2-Nitrotoluene
CAS No.	224185-19-7
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.03 g/mol
Synonyms	1-Bromo-4-fluoro-2-methyl-5-nitrobenzene; 2-Methyl-4-bromo-5-fluoronitrobenzene; Toluene, 4-bromo-5-fluoro-2-nitro-; 5-Fluoro-4-bromo-2-nitrotoluene; 4-Bromo-5-fluoro-2-methylnitrobenzene; 2-Nitro-4-bromo-5-fluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Fluoro-2-Nitrotoluene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.