Description

(2E)-4-(3-Hydroxy-2-Nitrophenyl)-4-Oxo-2-Butenoic Acid Methyl Ester is a high-purity, synthetic organic compound featuring a conjugated enone system attached to a nitrophenol derivative, making it a valuable intermediate for advanced chemical synthesis. This compound is critical for research and development in fine chemical and pharmaceutical manufacturing, where precise molecular architecture is required. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those with complex phenolic or quinone structures.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators due to its reactive nitrophenyl and α,β-unsaturated ester functionalities.
• Dye and Pigment Precursor: Acts as an intermediate in the production of specialized azo dyes and organic pigments, leveraging its nitro and hydroxy groups for color development.
• Organic Synthesis Research: Employed in academic and industrial laboratories for studying Michael addition reactions, cyclization processes, and as a precursor for heterocyclic compounds.
• Material Science: Investigated as a monomer or cross-linking agent for developing advanced polymers with specific optical or electronic properties.

Basic Information

Product Name	(2E)-4-(3-Hydroxy-2-Nitrophenyl)-4-Oxo-2-Butenoic Acid Methyl Ester
CAS No.	224044-67-1
Molecular Formula	C11H9NO6
Molecular Weight	251.19 g/mol
Synonyms	Methyl (2E)-4-(3-hydroxy-2-nitrophenyl)-4-oxobut-2-enoate; 4-(3-Hydroxy-2-nitrophenyl)-4-oxo-2-butenoic acid methyl ester; 2-Butenoic acid, 4-(3-hydroxy-2-nitrophenyl)-4-oxo-, methyl ester, (2E)-; Methyl 4-(3-hydroxy-2-nitrophenyl)-4-oxo-2-butenoate
EINECS	Contact for details

Quality Control

Every batch of (2E)-4-(3-Hydroxy-2-Nitrophenyl)-4-Oxo-2-Butenoic Acid Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets your specific research or production requirements. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.