Description

Ethyl 7-Bromo-3-Oxo-3,4-Dihydroquinoxaline-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a distinct quinoxaline core structure. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its versatile bromo and ester functional groups.
• Agrochemical Development: Serves as a building block for novel fungicides, herbicides, and insecticides, leveraging the bioactivity of the quinoxaline scaffold.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to construct complex heterocyclic systems.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in API manufacturing.

Basic Information

Product Name	Ethyl 7-Bromo-3-Oxo-3,4-Dihydroquinoxaline-2-Carboxylate
CAS No.	223711-74-8
Molecular Formula	C₁₁H₉BrN₂O₃
Molecular Weight	297.11 g/mol
Synonyms	7-Bromo-3-oxo-3,4-dihydroquinoxaline-2-carboxylic acid ethyl ester; Ethyl 7-bromo-3-oxo-1,4-dihydroquinoxaline-2-carboxylate; 2-Quinoxalinecarboxylic acid, 7-bromo-3,4-dihydro-3-oxo-, ethyl ester; 7-Bromo-3-oxo-1,4-dihydro-2-quinoxalinecarboxylic Acid Ethyl Ester; 7-Bromo-3-oxo-3,4-dihydro-2-quinoxalinecarboxylate ethyl ester; EBODQC; 223711-74-8
EINECS	Contact for details

Quality Control

Our Ethyl 7-Bromo-3-Oxo-3,4-Dihydroquinoxaline-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.